[HTML][HTML] Pathophysiological basis and rationale for early outpatient treatment of SARS-CoV-2 (COVID-19) infection

PA McCullough, RJ Kelly, G Ruocco, E Lerma… - The American journal of …, 2021 - Elsevier
Approximately 9 months of the severe acute respiratory syndrome coronavius-2 (SARS-CoV-
2 [COVID-19]) spreading across the globe has led to widespread COVID-19 acute
hospitalizations and death. The rapidity and highly communicable nature of the SARS-CoV-
2 outbreak has hampered the design and execution of definitive randomized, controlled
trials of therapy outside of the clinic or hospital. In the absence of clinical trial results,
physicians must use what has been learned about the pathophysiology of SARS-CoV-2 …